Typhoon Said to Have Killed Hundreds in Philippines


Karlos Manlupig/Associated Press


Residents assessed the damage to their homes on the southern Philippine island of Mindanao on Tuesday after a typhoon struck.







MANILA – Rescue teams were trying to reach isolated villages in the southern Philippines on Wednesday after a powerful out-of-season typhoon tore through the region, leaving more than 200 people dead, according to local officials.









NASA

Typhoon Bopha moved toward the Philippines on Monday.






Karlos Manlupig/Associated Press

Relatives mourned in New Bataan on Wednesday.






Typhoon Bopha packed winds of up to 100 miles per hour when it struck Tuesday, bringing torrential rains that flattened entire villages, leaving thousands homeless, as well as washing out roads and bridges needed by rescue personnel trying to reach stricken regions.


Officials in two of the hardest-hit areas told local news outlets that the death toll had surpassed 200, though the national government said Wednesday afternoon that just over 100 deaths had been confirmed. Officials said that figure was likely to increase as rescue teams reached devastated remote villages. In one area alone, Compostela Valley, more than 200 people were missing.


The storm was weakening and leaving the Philippines on Wednesday. The Philippines is hit by more than 20 powerful tropical storms per year, but Bopha struck remote communities off the usual storm path that are not accustomed to such strong typhoons.  


In December of last year, Tropical Storm Washi killed more than 1,200 people and left hundreds of thousands homeless. Officials this year called for mandatory early evacuations of vulnerable communities.


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Facebook just realized it made a horrible mistake












Facebook (FB) announced on Tuesday that it will begin opening Facebook Messenger to consumers who do not have a Facebook account, starting in countries like India and South Africa, and later rolling out the service in the United States and Europe. This is a belated acknowledgement of a staggering strategic mistake Facebook made two years ago. That is when the messaging app competition was still wide open and giants like Facebook or Google (GOOG) could have entered the competition. WhatsApp, the leading messaging app firm, had just 1 million users as late as December 2009. By the end of 2010, that number had grown to 10 million. Right now, it likely tops 200 million, though there is no current official number on the matter.


SMS usage started peaking in countries like Netherlands in 2010. Companies like Facebook, Twitter and Google were being offered a giant new market on a silver platter with more than 3 billion consumers worldwide use texting on their phones and many of them started drifting away from basic SMS towards IP-based alternatives a few years ago. None of the behemoths saw or understood the opportunity.












They allowed the mobile messaging market to turn into a free-for-all between tiny start-ups like KakaoTalk, Kik, Viber, WhatsApp, etc. And with astonishing speed, the global market picked a winner and rallied around it. Back in early 2011, there was serious debate about the relative merits of different messaging apps and which one might ultimately edge ahead.


In December 2012, the competitive landscape is stark. Kik is not a Top 5 app in any country in the world. Viber is a Top 5 app in 21 countries, but they are countries like Barbados, Nepal and Tajikistan. WhatsApp is a Top 5 app in 141 countries, including the U.S,, U.K., Germany, Brazil and India. The only real weakness of WhatsApp lies in China, Japan and South Korea, where local champions still lead. But those local apps have zero chance of breaking out of their home markets.


The mobile messaging app competition is over. It turned into a red rout sometime during late 2011 and WhatsApp has emerged as the sole beneficiary of a textbook case of the network effect.


Facebook, Google and Twitter threw away their golden chance to create an SMS killer and grab hold of a billion users globally. It would have been so easy and cheap to develop a simple texting app in 2009, leverage the current user base of any of the IT giants and then watch the app soar to global prominence.


And it is so very, very hard to do now. Dislodging WhatsApp now would mean neutralizing a smartphone market penetration advantage that is hitting 80% in some markets. People often ask me why I’m so fixated on WhatsApp and the answer is simple: it’s the most popular and important mobile app in the world. And it beat Facebook, Twitter, Google and other major companies before they even realized there was an important war being waged.


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Social Media News Headlines – Yahoo! News


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Bret Bielema leaves Wisconsin for Arkansas


FAYETTEVILLE, Ark. (AP) — In its second stunning hiring this year, Arkansas tabbed Wisconsin coach Bret Bielema to take over a program that went into a tailspin after former coach Bobby Petrino was fired for hiring his mistress to work in the athletic department.


The Razorbacks released a statement Tuesday night saying Bielema will leave the Badgers after seven seasons. The announcement came minutes after he met with players at Wisconsin, and he'll be introduced at an afternoon news conference in Fayetteville on Wednesday.


"His tough, aggressive style of play has been successful and will be appealing to student-athletes and Razorback fans," Arkansas athletic director Jeff Long said in a statement. "He not only shares the vision and values for the future of Arkansas football, he embraces them."


A person familiar with the situation, who spoke on the condition of anonymity because the information hasn't been released publicly, says the deal is for six years and $3.2 million annually.


Bielema replaces interim coach John L. Smith, who was hired after Petrino was fired. Long announced after the season that Smith wouldn't return.


Barry Alvarez's hand-picked successor at Wisconsin, Bielema was 68-24 with the Badgers, with four double-digit-win seasons. He coached Wisconsin to a 17-14 victory over Arkansas at the Capital One Bowl in his first season.


He is leaving the Big Ten for the SEC and a Razorbacks program that opened the year with hopes of challenging for a national championship only to get mired in the Petrino scandal before stumbling to a 4-8 finish.


Bielema seems likely to bring a far different approach than what the Razorbacks have become accustomed to. Arkansas continually ranked among the Southeastern Conference's best passing teams under Petrino. Bielema, meanwhile, is known for his dominant offensive lines and slew of running backs.


"During my conversation with Jeff (Long), he described the characteristics for the perfect fit to lead this program," Bielema said in a statement. "It was evident we share the same mission, principles and goals."


Wisconsin running back Montee Ball tied Barry Sanders' long-standing single-season record of 39 touchdowns last year, and this year became the FBS career leader in touchdowns. He currently has 82 touchdowns after running for three Saturday night in the Big Ten title game against Nebraska — a 70-31 romp that secured the Badgers third straight trip to the Rose Bowl, where they will play Stanford on Jan. 1.


The 42-year-old Bielema was the defensive coordinator at Wisconsin for two years before being promoted to head coach in 2006. He played for Iowa and started his coaching career there as an assistant under Hayden Fry and later Kirk Ferentz.


"I was very surprised when Bret told me he was taking the offer from Arkansas," said Alvarez, now Wisconsin's athletic director. "He did a great job for us during his seven years as head coach, both on the field and off. I want to thank him for his work and wish him the best at Arkansas."


The Illinois native takes over a program still reeling following the Petrino scandal, one eager for stability and leadership.


"I'm excited about this decision," Arkansas cornerback Tevin Mitchel tweeted.


The Razorbacks improved their win total in four straight seasons under Petrino, including a 21-5 mark in 2010-11, and finished last season ranked No. 5. They had talked openly in the spring about competing for the school's first SEC championship and perhaps a national title.


Then came the April 1 motorcycle accident that led to Petrino's downfall. The married father of four initially lied about being alone during the wreck, later admitting to riding with his mistress — a former Arkansas volleyball player he had hired to work in the athletic department.


Smith, who had been an assistant the last three seasons at Arkansas under Petrino, was chosen by Long to guide a team that returned first-team All-SEC quarterback Tyler Wilson and a host of other key playmakers. The decision was lauded by the Razorbacks, who welcomed the personable Smith back with open arms.


The season hit the skids with a stunning overtime loss to Louisiana-Monroe on Sept. 8, starting a four-game losing streak that dropped Arkansas out of the rankings. The Razorbacks finished with the school's lowest win total since 2005, missing a bowl game for the first time since 2008.


"It's very difficult for me to believe that is not a bowl-eligible team," LSU coach Les Miles said following the Tigers' win over the Razorbacks in the season finale. "Watching the talent there, (it's) very capable."


Arkansas struggled to find its identity in the SEC after leaving the former Southwest Conference in 1992, but it appeared to have finally found just that under Petrino, who was hired after leaving the Atlanta Falcons during the season in 2007.


The Razorbacks turned into an offensive powerhouse under Petrino, leading the league in scoring and total offense last season. After winning 10 games and reaching the school's first BCS bowl game in 2010, losing to Ohio State, Arkansas won 11 games in 2011, capped by a Cotton Bowl win over Kansas State.


Still, Arkansas has yet to win the SEC, losing in the conference championship game three times.


While the country watched closely to see how Arkansas would react following Petrino's dismissal, Smith made headlines of his own throughout the season. The former Michigan State and Louisville coach filed for bankruptcy during the season, revealing $40.7 million in debt he blamed on bad land deals.


He was under far more fire from Arkansas fans for the mounting losses and it will be up to Bielema to turn things around in the loaded SEC West, with Alabama, LSU and now Texas A&M.


Long said during the season that the new coach would be tasked with building on the recent success at the school, which is looking into expanding the 72,000-seat Razorback Stadium and is currently building an 80,000-square-foot football operations center.


"The infrastructure in place at Arkansas shows the commitment from the administration to accomplish our goals together and I am excited to begin to lead this group of student-athletes," Bielema said. "This program will represent the state of Arkansas in a way Razorback fans everywhere will be proud of."


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Recipes for Health: Mediterranean Lentil Purée — Recipes for Health


Andrew Scrivani for The New York Times







The spicing here is the same as one used in a popular Egyptian lentil salad. The dish is inspired by a lentil purée that accompanies bread at Terra Bistro in Vail, Colo.




1/4 cup olive oil


1 large garlic clove, minced or pureed


1/2 teaspoon freshly ground cumin seeds


1/2 teaspoon freshly ground coriander seeds


1/8 teaspoon freshly ground cardamom seeds


1/4 teaspoon ground fenugreek seeds


3/4 cup brown or green lentils, washed and picked over


Salt and freshly ground pepper to taste


1 tablespoon plain low-fat yogurt (more to taste) or additional liquid from the lentils for a vegan version


Chopped cilantro for garnish (optional)


1. Combine 2 tablespoons of the olive oil and the garlic in a small frying pan or saucepan over medium heat. When the garlic begins to sizzle, add the spices. Stir together for about 30 seconds, then remove from the heat and set aside.


2. Place the lentils in a medium saucepan, cover by 1 to 2 inches with water, add a bay leaf, and bring to a boil. Add salt to taste, reduce the heat and cook until tender, 40 to 50 minutes. Remove the bay leaf. Taste and adjust salt. Place a strainer over a bowl and drain the lentils. Transfer to a food processor fitted with the steel blade.


3. Purée the lentils along with the garlic and spices. With the machine running add the additional olive oil and the garlic. Thin out as desired with the broth from the lentils. The purée should be very smooth; if it is dry or pasty, add more yogurt, broth, or olive oil. Taste and adjust salt. If desired add a few drops of lemon juice. Transfer to a bowl and sprinkle the cilantro over the top if desired, or spread directly on croutons or pita triangles.


Advance preparation: This will keep for four days in the refrigerator. You will probably need to moisten it with additional yogurt, olive oil or broth, and you may want to warm it and drizzle on a little more olive oil before serving.


Nutritional information per tablespoon: 31 calories; 2 grams fat; 0 grams saturated fat; 0 grams polyunsaturated fat; 1 gram monounsaturated fat; 0 milligrams cholesterol; 3 grams carbohydrates; 1 gram dietary fiber; 1 milligram sodium (does not include salt to taste); 1 gram protein


Martha Rose Shulman is the author of “The Very Best of Recipes for Health.”


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Los Angeles and Long Beach Ports to Reopen After Strike





LOS ANGELES — After an eight-day strike that crippled the ports of Los Angeles and Long Beach, clerical workers from a local office of the International Longshore and Warehouse Union on Tuesday night agreed to a new contract with the terminal operators at the ports. Union members will return to work Wednesday morning.




As the strike dragged into its second week, both sides had come under increasing pressure from local officials to end the dispute, which had threatened to derail the Southern California economy during the holiday season. Officials from the Port of Long Beach estimated that $650 million in trade has been idled each day of the strike and a federal mediator arrived on Tuesday to help broker a deal.


“I am pleased to announce that an agreement has been reached between labor and management that will bring to an end the eight-day strike that has cost our local economy billions of dollars,” Los Angeles Mayor Antonio Villaraigosa said in a statement released Tuesday night. “With the strike now ending, we must waste no time in getting the nation’s busiest port complex’s operations back up to speed.”


Although only about 600 clerical workers had been participating in the strike, they managed to shut down 10 of the 14 shipping container terminals at the two ports, because thousands of longshoremen from the union would not cross the picket lines.


“This victory was accomplished because of support from the entire family of 10,000 members” of the International Longshore and Warehouse Union in the harbor community, Robert McEllrath, the president of the union, said in a statement announcing the agreement.


Neither the union nor the terminal operators offered details of the new contract agreement on Tuesday night.


Steve Getzug, a spokesman for the Harbor Employers Association, which represents the terminal operators, said the union voted on the proposal from the employers on Tuesday shortly before the federal mediator arrived. He added that the deal included “some compromise on staffing issues that were important to the employers.”


“And, importantly, a deal has been reached,” Mr. Getzug said. “The longshoremen expected to return 7 a.m., ready to get the cargo moving again.”


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5 Nations Summon Israeli Envoys to Protest Settlement Plans





JERUSALEM — Britain, France, Spain, Sweden and Denmark summoned the Israeli ambassadors to their countries on Monday to protest Israel’s plans for increased settlement construction, an unusually sharp diplomatic step that reflected the growing frustration abroad with Israel’s policies on the Palestinian issue.




After the General Assembly voted overwhelmingly last week to upgrade the status of the Palestinians at the United Nations, Israel announced plans for 3,000 more housing units in contested areas of East Jerusalem and around the West Bank.


Israel raised particular alarms with its decision to continue planning and zoning work for the development of a contentious area known as E1, a project vehemently opposed internationally because it would partially separate the northern and southern West Bank, harming the prospects of a contiguous Palestinian state in that territory.


The move raised questions in Israel about whether the country’s leaders were putting domestic political interests ahead of its foreign relations, with Israeli elections scheduled for late January.


“Bibi had to do something” in response to the United Nations vote, said Prof. Shmuel Sandler of the Begin-Sadat Center for Strategic Studies at Bar-Ilan Universiy, referring to the prime minister of Israel, Benjamin Netanyahu, by his nickname, “first because he is Bibi and second because of the elections.”


Mr. Sandler said that Mr. Netanyahu, a conservative, was making the mistake of competing against those farther to the right, adding, “But I don’t think he expected such a reaction” internationally.


Yet Israel remained defiant. The prime minister’s office issued a statement on Monday, saying, “Israel will continue to stand for its essential interests, even in the face of international pressure, and there will be no change in the decision it has taken.”


A press officer for United Nations Secretary General Ban Ki-moon said in a statement on Sunday that construction in E1 “would represent an almost fatal blow to remaining chances of securing a two-state solution.”


European countries long opposed to Israeli settlement construction went beyond their usual statements of condemnation. The countries that called in the Israeli ambassadors “expressed their strong protests about the announced settlement plans,” said Yigal Palmor, the spokesman for the Israeli Foreign Ministry.


Mr. Palmor said that the Israeli ambassadors told their hosts that Israel had been warning for months that the Palestinian bid at the United Nations would not go unanswered and that it would have implications.


Israel has described the bid as a unilateral Palestinian step that violates previous signed agreements. The Palestinians have long refused to negotiate with Israel without a halt in settlement construction.


France, Spain, Sweden and Denmark voted for the Palestinian upgrade, while Britain abstained. Although Israel had expected the resolution to pass, officials here expressed disappointment over the lack of support from several friendly European nations. Israel was particularly surprised by Germany’s decision to abstain in the vote, having expected Germany to go with Israel.


Prime Minister Benjamin Netanyahu is scheduled to visit Germany this week. Despite the so-called special relationship between Israel and Germany, Chancellor Angela Merkel has not minced words about her opposition to Israeli settlement construction in the past.


Philippe Lalliot, a spokesman for the French Foreign Ministry, said in a statement on Monday, “Settlement activity is illegal under international law, hurts the confidence necessary for a return to dialogue and constitutes an obstacle to a just peace founded on the two-state solution.”


The British Foreign Office said that it deplored the Israeli settlement plans and that it had called on the Israeli government to reverse the decision.


But Israeli officials denied that the government’s policies were isolating Israel.


“It is well known that Europe and Israel have a different approach on settlements,” said one Israeli official, speaking on the condition of anonymity. “There is nothing new here. If European countries would have behaved differently in their vote at the United Nations last week,” he continued, “we may have reacted differently.”


Analysts here said that after showing strong support for Israel during its military campaign last month against Hamas, the Islamic militant group that controls Gaza, European countries had felt the need to bolster the more moderate Palestinian wing led by President Mahmoud Abbas in its United Nations bid.


At the weekly cabinet meeting on Sunday, Mr. Netanyahu said, “Today we are building and we will continue to build in Jerusalem and in all areas that are on the map of the strategic interests of the State of Israel.”


But beyond the tit-for-tat measures set off by the United Nations vote, analysts pointed to a trend of deteriorating relations between Israel and Europe in particular.


“That is because the top-level people making decisions here in recent years are completely insular and out of touch with the rest of the world, especially regarding the Palestinians and the settlements,” said Mark Heller, a foreign-policy analyst at the Institute for National Security Studies at Tel Aviv University. “Self-righteousness may be good for domestic politics,” he said, “but it is not a policy.”


At the United Nations General Assembly on Thursday, 138 nations voted in favor of upgrading the status of the Palestinians and 41 abstained. The nine that voted against it were Israel, the United States, Canada, the Czech Republic, the Marshall Islands, Micronesia, Nauru, Panama and Palau.


Scott Sayare contributed reporting from Paris.



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Facebook voting begins on Instagram data-sharing, email privacy












SAN FRANCISCO (Reuters) – Facebook Inc opened the polls on Monday for its roughly 1 billion users to vote on a variety of changes to the social network‘s policies, including a proposal to scrap the user voting system that Facebook introduced in 2009.


Facebook also said it had “clarified” some of the proposed changes, specifying that a new policy allowing it to share user data with recently acquired photo-application Instagram will be carried out in compliance with applicable laws and that Facebook will seek user consent when necessary.












The proposed changes, which Facebook announced on November 21, generated roughly 89,000 user comments as well as concerns from some privacy-advocacy groups and a request for more information from the Data Protection Commission in Ireland, where Facebook’s European business has its headquarters.


“Based on your feedback and after consultation with our regulators, including the Irish Data Protection Commissioner‘s Office, we’ve further clarified some of our proposals,” said Elliot Schrage, Facebook Vice President of Communications, Public Policy and Marketing in a post on Facebook’s company blog on Monday.


Facebook is proposing to eliminate the 4-year-old system that allows users to vote on changes to its governance policies. The company says the voting system hasn’t functioned as intended and is no longer suited to its current situation as a large publicly traded company subject to oversight by various regulatory agencies.


Facebook said on Monday that it would incorporate user suggestions for creating new tools to “enhance communication” on privacy and governance matters.


Another proposal would loosen the restrictions on how members of the social network can contact other members using the Facebook email system. The company said it planned to replace the “Who can send you Facebook messages” setting with new filters for managing incoming messages.


Facebook’s potential information sharing with Instagram, a photo-sharing service for smartphone users that it bought in October, flows from proposed changes that would allow the company to share information between its own service and other businesses or affiliates it owns.


The change could open the door for Facebook to build unified profiles of its users that include people’s personal data from its social network and from Instagram, similar to recent moves by Google Inc.


Facebook said on Monday that the proposed change was “standard in the industry” and “promotes the efficient and effective use of the services Facebook and its affiliates,” such as allowing users in the U.S. to interact with users in Europe.


“This provision covers Instagram and allows us to store Instagram’s server logs and administrative records in a way that is more efficient than maintaining totally separate storage systems,” the company wrote in a separate post on its website Monday titled “explanation of changes”.


“Where additional consent of our users is required, we will obtain it,” Facebook said.


Facebook users have until December 10 to vote on the policies using a special third-party application provided by Facebook and Facebook said the results will be certified by an independent auditor.


The vote is only binding if at least 30 percent of users take part, and two prior votes never reached that threshold.


(Reporting By Alexei Oreskovic; editing by Andrew Hay)


Tech News Headlines – Yahoo! News


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NFC East wide open after Redskins top Giants 17-16

LANDOVER, Md. (AP) — There was the fumble by Robert Griffin III that turned into a Washington Redskins touchdown. There was the fumble by teammate Alfred Morris that led to a melee of leg-pulling followed by a kick to the midsection and something dangerously close to a stomp.

The quartet of flawed teams that make up the NFC East sure do make things interesting.

The division title that seemingly belonged to the New York Giants is up for grabs after their 17-16 loss Monday night to the Redskins, who are back in the running thanks to a rookie quarterback and a three-game winning streak.

"We had an opportunity here today," New York coach Tom Coughlin said. "But now there's one team with seven and two teams with six wins. There's four games to go."

That about sums it up.

Now that the Giants (7-5) have lost three of four, the Redskins (6-6) and Cowboys (6-6) are squarely in the hunt despite mediocre records. Washington has dispatched each of its division rivals — Philadelphia, Dallas and now New York — one by one over the last three weeks to recover from a 3-6 start that prompted coach Mike Shanahan to talk about evaluating players for future seasons.

"We know that our backs are against the wall," said Griffin, whose Redskins host Dallas in what they hope will be a meaningful season finale. "And even though we won tonight, our backs are still against the wall."

It'll be hard to count the Redskins out as long as Griffin is on the field. He completed 13 of 21 passes for 163 yards and a go-ahead, 8-yard touchdown to Pierre Garcon in the fourth quarter to finish with a 101.9 passer rating. He also ran for 72 yards to get to 714 for the season, breaking Cam Newton's NFL record for a rookie quarterback.

It was his sixth game with a 100-plus passer rating, his eighth without an interception — and his second in which one of his fumbles turned into a Redskins score.

On the way to the turf after a 12-yard run, Griffin was stripped by Stevie Brown — but the ball flew right to teammate Joshua Morgan 3 yards upfield. Morgan then ran 13 yards for a first-quarter touchdown no one would ever diagram on a whiteboard.

"We didn't run it in practice because we wanted to save it for the game," Griffin said with a grin. "I knew he was going to be there for it. ... Joshua did a good job being in the spot where he was supposed to be."

The game's other fumble was just as chaotic — and a little scary. After Morris was stripped during a third-quarter run, New York defensive tackle Linval Joseph yanked at Redskins center Will Montgomery's leg while players were fighting for the ball in the pile.

Montgomery kicked out in response, a swipe that Joseph said hit him in the groin.

"I was just trying to get my leg loose," Montgomery said.

Joseph then stomped at Montgomery, appearing to pull back at the last second but still making contact.

"It took me everything not to kick him back because I didn't want hurt the team, and I didn't want to get fined and none of that," Joseph said. "I started, then I stopped."

Joseph and a Redskins player were whistled for offsetting unnecessary roughness penalties.

Morris finished with 124 yards, reaching 1,106 for the season to break Reggie Brooks' franchise rookie rushing record of 1,063, set in 1993. Garcon caught eight passes for 106 yards, showing no signs of the painful toe injury that forced him to miss six of the season's first nine games.

Eli Manning completed 20 of 33 passes for 280 yards and a touchdown, and Ahmad Bradshaw ran for 103 yards on 24 carries for the Giants. Victor Cruz, who caught the game-winning score when the teams met in the Meadowlands in October, had five catches for 104 yards.

The Giants moved the ball well, but they only managed three field goals by Lawrence Tynes and one touchdown — Manning's 4-yard pass to Martellus Bennett late in the second quarter.

Tynes also missed a 43-yard field goal, and the Giants were uncharacteristically penalty-prone, getting flagged nine times for 73 yards. New York led 13-10 at the half, but scored only three more points.

"This is not real complicated. I don't know what happened in the second half," Coughlin said. "We certainly didn't come out and play. Penalties. Sloppy football."

NOTES: The Giants had won 26 in a row on the road when holding a halftime lead. They last failed to finish the job in 2006 against Tennessee. ... The Redskins snapped a 10-game home losing streak in Monday night games. ... Shanahan got his 171st win (regular and postseason), tying him with Redskins' Hall of Fame coach Joe Gibbs for 12th all time. ... New York S Tyler Sash left the game with a hamstring injury, and RT Sean Locklear was carted off in the fourth quarter with a knee injury.

___

Follow Joseph White on Twitter: http://twitter.com/JGWhiteAP

___

Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

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Generic Drug Makers Facing Squeeze on Revenue


They call it the patent cliff.


Brand-name drug makers have feared it for years. And now the makers of generic drugs fear it, too.


This year, more than 40 brand-name drugs — valued at $35 billion in annual sales — lost their patent protection, meaning that generic companies were permitted to make their own lower-priced versions of well-known drugs like Plavix, Lexapro and Seroquel — and share in the profits that had exclusively belonged to the brands.


Next year, the value of drugs scheduled to lose their patents and be sold as generics is expected to decline by more than half, to about $17 billion, according to an analysis by Crédit Agricole Securities.“The patent cliff is over,” said Kim Vukhac, an analyst for Crédit Agricole. “That’s great for large pharma, but that also means the opportunities theoretically have dried up for generics.”


In response, many generic drug makers are scrambling to redefine themselves, whether by specializing in hard-to-make drugs, selling branded products or making large acquisitions. The large generics company Watson acquired a European competitor, Actavis, in October, vaulting it from the fifth- to the third-largest generic drug maker worldwide.


“They are certainly saying either I need to get bigger, or I need to get ‘specialer,’ ” said Michael Kleinrock, director of research development at the IMS Institute for Healthcare Informatics, a health industry research group. “They all want to be special.”


As one consequence of the approaching cliff, executives for generic drug companies say, they will no longer be able to rely as much on the lucrative six-month exclusivity periods that follow the patent expirations of many drugs. During those periods, companies that are the first to file an application with the Food and Drug Administration, successfully challenge a patent and show they can make the drug win the right to sell their version exclusively or with limited competition.


The exclusivity windows can give a quick jolt to companies. During the first nine months of 2012, sales of generic drugs increased by 19 percent over the same period in 2011, to $39.1 billion from $32.8 billion, according to Michael Faerm, an analyst for Credit Suisse. Sales of branded drugs, by contrast, fell 4 percent during the same period, to $174.2 billion from $181.3 billion.


But those exclusive periods also make generic drug makers vulnerable to the fickle cycle of patent expiration. “The only issue is it’s a bubble, too,” said Mr. Kleinrock. He said next year, the generic industry would enter a drought that was expected to last about two years.  Of the drugs that are becoming generic, fewer have exclusivity periods dedicated to a single drug maker.


In 2013, for example, the antidepressant Cymbalta, sold by Eli Lilly, is scheduled to be available in generic form. But more than five companies are expected to share in sales during the first six months, according to a report by Ms. Vukhac.


Heather Bresch, the chief executive of Mylan, the second-largest generics company in the United States, said Wall Street analysts were obsessed with the issue. “I can’t go anywhere without being asked about the patent cliff, the patent cliff, the patent cliff,” she said. “The patent cliff is one aspect of a complex, multilayered landscape, and I think each company is going to face it differently.”


Jeremy M. Levin, the chief executive of Teva Pharmaceuticals, the largest global maker of generic drugs, agreed. “The concept of exclusivity — where only one generic player could actually make money out of the unique moment — has diminished,” he said. “In the absence of that, many companies have had to really ask the question, ‘How do I really play in the generics world?’ ”


For Teva, Mr. Levin said, he believes the answer will be both its reach  — it sells 1,400 products, and one in six generic prescriptions in the United States is filled with a Teva product  — and what he says is a reputation for making quality products. That focus will be increasingly important, he said, given recent statements by the F.D.A. that it intends to take a closer look at the quality of generic drugs. Mr. Levin also said he planned to cut costs, announcing last week that he intended to trim from $1.5 to $2 billion in expenses over the next five years.


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India Ink: A Conversation With: India's Chief Climate Change Negotiator

DOHA, Qatar – With one week left for the U.N. climate change talks to conclude, developed and developing countries remain at odds on how to solve the crisis being linked to the recent spate of extreme weather events that have claimed lives and destroyed property worth billions of dollar.

India has agreed to a take on legally binding obligations after 2020. But for the next eight years, New Delhi wants developed countries to honor their commitments under previous agreements including significantly bringing down their carbon dioxide emissions as well as providing finance and technology to developing countries. Emissions of carbon dioxide hit a record high in 2011, with decreases by developing countries more than offset by increases from China and India.

As discussions heat up here in Doha, India’s chief negotiator, Meera Mehrishi, spoke to India Ink on the contentious issues playing out in the halls of the mammoth Qatar National Convention Center, where delegates from 194 countries have gathered.

Hurricane Sandy, which hit the United States in late October, raised a global alarm about the consequences of climate change. Why don’t these talks reflect urgency for action?

After Hurricane Sandy, I thought the point of view of the Western world would change a little bit. I don’t see that happening. Climate change is becoming a reality because we are facing weather that we have never faced earlier across the world, be it a developed or developing country. And I think at conferences like this, we should have a positive outcome and not just keep postponing things till the next meeting.

A senior negotiator from the United States, Jonathan Pershing, said last week that talks in Doha must phase out obligations under older agreements. How do you react to that?

I know.  But Jonathan Pershing, I find to be a very reasonable man. And yes, I heard that he had made this very strong comment earlier. But we have spoken to the American delegation and they are quite willing to sit down and talk about issues. At least, they are not completely throwing them out of the window. So let us see, while we keep the conversation going, what we are able to keep on the table.

What are India’s stakes at these talks?

Our country is being impacted by climate change. We have had freaky weather in India. The monsoons that used to come in July have started coming in September. The farmers are finding it difficult now because they continue to plant during what they perceive to be the monsoon season. We are losing our crop. It’s going to have huge repercussions on food security in the country. It’s going to take them time to adapt.  And we don’t know what will happen after five to ten years. How often will farmers try to adapt? It will be very difficult.

Last week, you asked the developed world to take higher emission cuts. Can differences between developed and developing countries be resolved in this remaining week?

I think attempts are being made to bridge the divide. Though we are having formal meetings, but we are having a lot of informal consultations. Countries are meeting bilaterally. Very contentious issues are being discussed. And I think everyone is keen to see a Doha outcome.

I think European Union in a meeting mentioned that they were willing to raise their targets to 30 percent. There are some conditionalities that still have to be looked at.  But there is a possibility of European Union raising their targets.

Could you elaborate on the contentious issues?

Well, one that is very contentious is the intellectual property rights-related issue.  Developing countries have been pressing that technology gets transferred from developed to developing countries. We are hoping that developed countries transfer that technology without us having to pay the royalty. But that’s not working out because there are very rigid views from that side because the private sector is involved. The private sector has spent a lot on research and development and I guess they would like some return on it. But then without technology, it will be difficult for developing countries to meet their targets.

Any other particularly tough issue?

Unilateral measures are the other problem for us. Do not take decisions bilaterally that impact other countries. The EUETS [European Union Emissions Trading System] is an example. You [the European Union] impose a tax on civil aviation on airlines that are coming into the European Union. But you’re imposing taxes on flights through their own airspace — that is not European Union airspace. And it had to be discussed keeping the principles of the UNFCCC [United Nations Framework Convention on Climate Change] in view. Now that was not done. It was just announced that we are imposing this tax. They have stopped the clock now and it will be discussed in ICAO [International Civil Aviation Organization]. But we are hoping to see that the principles of the convention are kept in mind by the European Union. And we also want to see that no more unilateral actions are taken.

What about money? Is there any movement on mobilizing $100 billion by 2020?

We have set up institutions. We have a Green Climate Fund but how much money is going to come into that and from where … nobody is willing to make that commitment. That is a major problem for us.

On the finance problem, India and China are proud of their growth stories but they still want a slice of the funds. Does India really need this money?

But our growth story has stopped.  The growth is now 5.5 percent. I won’t say that we are desperate for money but it is always welcome. And in these multilateral forums, we are part of the larger group, G77 + China, we all speak with one voice.

Speaking of groups, how united is the BASIC [Brazil, South Africa, India and China] group now? There have been rumors of divisions inside, especially South Africa having its own agenda.

I don’t think the rumors are true. Because as BASIC, we have been meeting regularly for the last one year. And there are a lot of commonalities among the four countries. Yes, South Africa may have its own agenda. We may have our own agenda. Discussions maybe a little strong sometimes but we come to a consensus. I don’t think the unity of BASIC is going to break. Not now at all.

What commonalities keep BASIC together?

All four countries are developing rapidly. Growth of all four countries has slowed down. We also know that post-2020 to take on any kind of targets, we need to allow our countries to develop now. To develop we need finance and technology … that is where we come together. The idea is that we have to have a good sort of life for people in our countries. China’s growth has slowed down. Brazil is doing very well. But Brazil again has pockets in their country that like us have to develop rapidly.

This interview has been lightly edited and condensed.

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